Abstract: A novel photovoltaic-thermal (PVT) system adopting a lightweight aluminum alloy parallel full-channel collector was developed. Through a combination of experiments and simulations, the thermoelectric performance of the PVT system and the temperature distribution of the PV module were investigated using 40% ethylene glycol solution and 3% Al₂O₃-water nanofluidat at different volume flow rates. Results show that at the same volume flow rate, the exergy of the 40% ethylene glycol solution is higher than that of the 3% Al₂O₃-water nanofluid, but the overall PVT efficiency using it as the cooling working fluid is lower than that of the nanofluid. Increasing the volume flow rate of working fluid can reduce the standard deviation of the PV module's temperature field, thereby improving the uniformity of its temperature distribution. The 3% Al₂O₃-water nanofluid outperforms the 40% ethylene glycol solution in terms of the temperature uniformity of the PV module, but its application area is limited due to its higher condensation temperature.